1H-Indole-2-carboxylic acid, 4-nitro-
4-Nitro-1H-indole-2- carboxylic acid
CAS: 16732-60-8
Molecular Formula: C9H6N2O4
1H-Indole-2-carboxylic acid, 4-nitro- - Names and Identifiers
| Name | 4-Nitro-1H-indole-2- carboxylic acid |
| Synonyms | 4-Nitro-1H-indole-2- carboxylic acid 1H-Indole-2-carboxylic acid, 4-nitro- |
| CAS | 16732-60-8 |
1H-Indole-2-carboxylic acid, 4-nitro- - Physico-chemical Properties
| Molecular Formula | C9H6N2O4 |
| Molar Mass | 206.16 |
| Density | 1.632±0.06 g/cm3(Predicted) |
| Melting Point | 317-318 °C |
| Boling Point | 520.8±30.0 °C(Predicted) |
| Appearance | Solid |
| Color | Yellow |
| pKa | 3.91±0.30(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD07374290 |
1H-Indole-2-carboxylic acid, 4-nitro- - Upstream Downstream Industry
1H-Indole-2-carboxylic acid, 4-nitro- - Introduction
4-Nitro-1H-indole-2- carboxylic acid is an organic compound with the chemical formula C9H6N2O5. It is a yellow crystalline powder with a strong smell. The following are some information about the properties, uses, preparation and safety of the compound:
Nature:
-Appearance: Yellow crystal powder
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), Dimethyl Formamide (DMF) and ethanol
-Melting point: About 200-205 ° C
-Stability: relatively stable under dry conditions, but sensitive to light and heat
Use:
-4-nitro-1h-indole-2-carboxylic acid is often used as a chemical intermediate for the synthesis of various organic compounds and drugs in the pharmaceutical field
-It can also be used as a substrate or catalyst for organic synthesis reactions
Method:
-4-nitro-1h-indole-2-carboxylic acid can be obtained by carboxylation of 4-nitro-1h-indole
-A commonly used synthesis method is to react a mixture of 4-nitro-1H-indole and methylene chloride (CH2Cl2) under reaction conditions to obtain the product
-The use of acid and base catalysts may be required in the synthesis
Safety Information:
-4-nitro-1h-indole-2-carboxylic acid may cause irritation to the eyes, skin and respiratory tract and should be carefully touched
-During operation or storage, avoid contact with oxidants, strong acids, strong bases and combustibles
-When performing experiments or operations, closely observe laboratory safety practices and wear appropriate protective equipment, such as lab gloves and glasses
Nature:
-Appearance: Yellow crystal powder
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), Dimethyl Formamide (DMF) and ethanol
-Melting point: About 200-205 ° C
-Stability: relatively stable under dry conditions, but sensitive to light and heat
Use:
-4-nitro-1h-indole-2-carboxylic acid is often used as a chemical intermediate for the synthesis of various organic compounds and drugs in the pharmaceutical field
-It can also be used as a substrate or catalyst for organic synthesis reactions
Method:
-4-nitro-1h-indole-2-carboxylic acid can be obtained by carboxylation of 4-nitro-1h-indole
-A commonly used synthesis method is to react a mixture of 4-nitro-1H-indole and methylene chloride (CH2Cl2) under reaction conditions to obtain the product
-The use of acid and base catalysts may be required in the synthesis
Safety Information:
-4-nitro-1h-indole-2-carboxylic acid may cause irritation to the eyes, skin and respiratory tract and should be carefully touched
-During operation or storage, avoid contact with oxidants, strong acids, strong bases and combustibles
-When performing experiments or operations, closely observe laboratory safety practices and wear appropriate protective equipment, such as lab gloves and glasses
Last Update：2024-04-09 15:18:03
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Raw Materials for 1H-Indole-2-carboxylic acid, 4-nitro-
(E)-ethyl 2-(2-(3-nitrophenyl)hydrazono)propanoate
ETHYL 6-NITRO-1H-INDOLE-2-CARBOXYLATE
ETHYL 4-NITRO-1H-INDOLE-2-CARBOXYLATE
6-NITRO-1H-INDOLE-2-CARBOXYLIC ACID
(E)-ethyl 2-(2-(3-nitrophenyl)hydrazono)propanoate
3-Nitroaniline
ETHYL 6-NITRO-1H-INDOLE-2-CARBOXYLATE
ETHYL 4-NITRO-1H-INDOLE-2-CARBOXYLATE
6-NITRO-1H-INDOLE-2-CARBOXYLIC ACID
(E)-ethyl 2-(2-(3-nitrophenyl)hydrazono)propanoate
3-Nitroaniline